产品名称：Chloromethylation of calixarenes 氯甲基化杯芳烃

Chloromethylation of calixarenes involves the introduction of chloromethyl (-CH2Cl) groups onto the calixarene structure. This chemical modification can impart new properties and functionalities to calixarenes, expanding their potential applications. Here’s an overview of the chloromethylation process and its implications:

Chloromethylation Process

1. Reagent: The chloromethylation reaction typically involves the use of chloromethyl methyl ether (CMME) or formaldehyde with hydrochloric acid under suitable conditions. CMME is often preferred due to its controlled reactivity and ease of handling.

2. Reaction Conditions: The chloromethylation reaction is usually carried out under acidic conditions to facilitate the formation of the chloromethyl group. Common conditions include the use of hydrochloric acid and an appropriate solvent, such as dichloromethane or chloroform.

3. Mechanism: Chloromethylation involves the nucleophilic attack of the aromatic ring of the calixarene by the chloromethyl group from CMME or formaldehyde. This results in the substitution of a hydrogen atom on the aromatic ring with a chloromethyl group.

Implications and Applications

• Functionalization: Chloromethylation introduces chloromethyl groups onto the calixarene structure, which can serve as versatile intermediates for further functionalization. These groups can undergo various chemical reactions to introduce other functional groups, such as amino, hydroxyl, or carboxyl groups.

• Solubility and Reactivity: Chloromethylated calixarenes often exhibit improved solubility in organic solvents compared to their parent compounds, which enhances their utility in organic synthesis and applications.

• Crosslinking and Polymerization: Chloromethyl groups can participate in crosslinking reactions or polymerization processes, leading to the formation of new materials with controlled properties. This makes chloromethylated calixarenes valuable in material science and polymer chemistry.

• Ion Exchange and Adsorption: Functionalized calixarenes, including chloromethylated derivatives, are utilized as ion-exchange resins and adsorbents due to their ability to selectively bind metal ions and other polar compounds.

产地：西安

规格：1mg 5mg 10mg

纯度：99%

状态：固体/粉末

储藏条件：冷藏-20℃

温馨提示：仅用于科研，不能用于人体实验！

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小编：齐岳hao 2024年6月11日