产品名称:Calixarene-modified chitosans(CTS-CA)
Calixarene-modified chitosans (CTS-CA) refer to chitosan derivatives where calixarene molecules are covalently bonded or physically associated with chitosan. Chitosan itself is a natural polysaccharide derived from chitin, and it possesses unique properties such as biocompatibility, biodegradability, and low toxicity. Calixarenes, on the other hand, are macrocyclic molecules with a cup-shaped structure that can selectively bind to various guest molecules.
Key Features and Applications:
Structure and Modification:
Covalent Bonding: Calixarene molecules are chemically linked to chitosan chains, typically through functional groups like hydroxyl, amine, or carboxyl groups.
Physical Association: Calixarenes may also be physically adsorbed or complexed onto the surface or within the chitosan matrix.
Properties:
Molecular Recognition: The incorporation of calixarenes enhances the molecular recognition capabilities of chitosan, allowing for selective binding and encapsulation of target molecules.
Biological Compatibility: Chitosan's biocompatibility is retained or enhanced by the modification, making CTS-CA suitable for biomedical applications.
Applications:
Drug Delivery Systems: CTS-CA can be used to encapsulate drugs within the calixarene cavities, protecting them from degradation and facilitating targeted delivery.
Biomedical Materials: They are used in tissue engineering, wound healing materials, and biomedical coatings due to their biocompatibility and controlled release properties.
Sensors and Detectors: The selective binding capabilities of calixarene-modified chitosans make them suitable for developing sensors and detectors for specific ions or molecules.
Environmental Applications: Used in water treatment and environmental remediation to remove pollutants due to their adsorption properties.
Synthesis and Functionalization:
Chemical Modifications: Various methods are employed to covalently attach calixarenes to chitosan, often involving multi-step organic synthesis techniques.
Tailoring Properties: By adjusting the structure and composition of CTS-CA, researchers can tailor their properties for specific applications, such as enhancing stability, solubility, or recognition specificity.
Research and Development:
Ongoing research focuses on optimizing the synthesis routes, exploring new applications, and understanding the mechanisms of interaction between calixarenes and chitosan.
The potential of CTS-CA in advanced drug delivery, biomedical implants, and environmental technologies continues to be explored, highlighting their versatility and potential impact in various fields.
产地:西安
规格:1mg 5mg 10mg
纯度:99%
状态:固体/粉末
储藏条件:冷藏-20℃
温馨提示:仅用于科研,不能用于人体实验!
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小编:齐岳hao 2024年6月11日