产品名称:Norbiotinamine
CAS:173401-47-3
Norbiotinamine refers to a modified form of biotin, where the valeric acid side chain of biotin is replaced by a norbornene moiety. This modification alters the chemical properties of biotin, particularly its reactivity towards certain conjugation reactions in chemical biology and bioconjugation applications.
Key Features and Applications:
Norbornene Modification: Norbornene is a bicyclic hydrocarbon with a reactive double bond, commonly used in bioorthogonal chemistry due to its selective reactivity with tetrazines or other strained alkynes via the Diels-Alder reaction.
Biotin Core: Retains the biotin moiety, which is essential for its high affinity binding to avidin or streptavidin proteins, widely used in various biological assays and detection methods.
Bioconjugation: Norbiotinamine is utilized in bioconjugation strategies where the norbornene group allows selective and efficient labeling of biomolecules with fluorescent probes, tags, or other functional groups.
Biological Applications: Used in cell biology, proteomics, and drug delivery research where precise and orthogonal labeling of biomolecules is required without interference with native biological processes.
Norbiotinamine thus represents a versatile tool in chemical biology, enabling specific and controlled labeling of biomolecules for various research and biotechnological applications.
产地:西安
规格:1mg 5mg 10mg
纯度:99%
状态:固体/粉末
储藏条件:冷藏-20℃
温馨提示:仅用于科研,不能用于人体实验!
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编辑:HAO 2024年7月1日