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DdeBiotin-Alkyne
发布时间:2024-07-02     作者:h   分享到:

产品名称:DdeBiotin-Alkyne

DdeBiotin-Alkyne refers to a compound where Dde (1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl) is linked to biotin via an alkyne functional group. This compound is often used in bioconjugation and chemical biology applications, specifically in the context of selective labeling of biomolecules such as proteins or nucleic acids.

Key Features and Applications:

  • Dde Protecting Group: The Dde group serves as a protecting group for the alkyne moiety, enabling selective deprotection under mild conditions.

  • Biotin: Biotin is a vitamin B derivative that binds strongly to avidin and streptavidin, making it useful for various affinity-based assays and purification methods.

  • Alkyne Functional Group: The alkyne group (–C≡CH) in DdeBiotin-Alkyne allows for bioorthogonal labeling reactions such as click chemistry. This feature facilitates specific and efficient conjugation with azides in biological systems.

Applications:

  • Bioconjugation: DdeBiotin-Alkyne is utilized to label biomolecules, including proteins and nucleic acids, via bioorthogonal chemistry techniques like click chemistry.

  • Protein Purification: Biotin's high affinity for avidin and streptavidin allows for the purification of biotinylated proteins using affinity chromatography.

  • Cellular Imaging: The alkyne group's bioorthogonal reactivity enables the visualization of specific biomolecules in live cells through fluorescence or other imaging modalities.

  • Drug Delivery Systems: This compound can be incorporated into drug delivery systems to target specific cells or tissues via bioorthogonal conjugation strategies.

产地:西安

规格:1mg 5mg 10mg

纯度:99%

状态:固体/粉末

储藏条件:冷藏-20℃

温馨提示:仅用于科研,不能用于人体实验!

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DdeBiotin-Alkyne

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编辑:HAO 2024年7月2日

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