常用名 血管紧张素II
英文名 Angiotensin II human acetate
CAS号 68521-88-0
分子式 C52H75N13O14
分子量 1106.23000
精确质量 1105.56000
PSA 443.64000
LogP 3.16040
外观性状 powder | orange
储存条件 存放在密封容器内,并放在阴凉,干燥处。储存的地方必须远离氧化剂。-20ºC保存。
稳定性 远离强酸,强碱。
水溶解性 H2O: 25 mg/mL, clear, colorless
Angiotensin II human (Angiotensin II) acetate is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human acetate plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human acetate stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human acetate induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis. Angiotensin II human acetate induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway[1][2][3][4].
包装:100mg,500mg,1g,10g,100g以及kg级别等公斤级大包装
纯度:99%
配送:惯例下常温**
包装:袋装
厂家:西安齐岳生物科技有限公司
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