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CAS:89226-75-5 Manidipine (dihydrochloride) 盐酸马尼地平 工艺优化
发布时间:2024-04-07     作者:zcy   分享到:

常用名 盐酸马尼地平

英文名 Manidipine hydrochloride

CAS号 89226-75-5

沸点 722ºC at 760 mmHg

熔点 211 °C(dec.)

分子式 C35H40Cl2N4O6

分子量 683.62

PSA 116.93000

LogP 6.48280

外观性状 固体;White to Light yellow powder to crystal

储存条件 室温,干燥,密封

水溶解性 水溶性:不溶

Manidipine dihydrochloride is a third-generation, lipophilic, orally active and highly vasoselective calcium channel antagonist (IC50 = 2.6 nM in guinea-pig ventricular cells) and acts as an antihypertensive agent. Manidipine effectively reduces blood pressure as well as improving insulin sensitivity, renal protection, and antiatherosclerotic activity. Manidipine also exerts anti-inflammatory activity mediated by NF-κB and antiviral activity against many flavivirus and negative-strand RNA viruses through the inhibition of calcium channel. Manidipine is widely applied to research of cardiovascular, metabolic disease and infection[1][2][3][4][5][6].

CAS:89226-75-5	Manidipine (dihydrochloride)	盐酸马尼地平   工艺优化

包装:100mg,500mg,1g,10g,100g以及kg级别等公斤级大包装

纯度:99%

配送:惯例下常温**

包装:袋装

厂家:西安齐岳生物科技有限公司

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西安齐岳生物科技有限公司具备批量生产能力和强大的研发能力,这样的双重优势可以确保企业不仅在满足市场需求上保持高效,同时也在产品创新和技术升级。能够提供100mg,500mg,1g,10g,100g以及kg级别等公斤级大包装。


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