常用名 哌唑嗪

英文名 Prazosin

CAS号 19216-56-9

密度 1.352g/cm3

沸点 638.4ºC at 760mmHg

熔点 278-280ºC

分子式 C19H21N5O4

分子量 383.40100

闪点 339.9ºC

精确质量 383.15900

PSA 107.68000

LogP 1.71760

蒸汽压 3.4E-16mmHg at 25°C

折射率 1.651

储存条件 库房通风低温干燥

"Prazosin is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder.

Target: Adrenergic Receptor

Prazosin, is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, andpanic disorder. It is an alpha-adrenergic blocker that is specific for the alpha-1 receptors. These receptors are found on vascular smooth muscle, where they are responsible for the vasoconstrictive action of norepinephrine. They are also found throughout the central nervous system. As of 2013, prazosin is off-patent in the US, and the FDA has approved at least one generic manufacturer.In addition to its alpha-blocking activity, prazosin is an antagonist of the MT3 receptor (which is not present in humans), with selectivity for this receptor over the MT1 and MT2 receptors.

Prazosin is orally active and has a minimal effect on cardiac function due to its alpha-1 receptor selectivity. However, when prazosin is initially started, heart rate and contractility go up in order to maintain the pre-treatment blood pressures because the body has reached homeostasis at its abnormally high blood pressure. The blood pressure lowering effect becomes apparent when prazosin is taken for longer periods of time. The heart rate and contractility go back down over time and blood pressure decreases."

包装：100mg，500mg，1g，10g，100g以及kg级别等公斤级大包装

纯度：99%

配送：惯例下常温**

包装：袋装

厂家：西安齐岳生物科技有限公司

关于我们：

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