常用名 甲磺酸帕珠沙星

英文名 Pazufloxacin mesylate

CAS号 163680-77-1

沸点 531.5ºC at 760 mmHg

熔点 >255°C (dec.)

分子式 C17H19FN2O7S

分子量 414.405

闪点 275.2ºC

精确质量 414.089691

PSA 157.30000

LogP 3.02510

外观性状 结晶固体

蒸汽压 4E-12mmHg at 25°C

储存条件 -20°C Freezer

水溶解性 水溶性：完全溶解；可溶于：甲醇,二甲基甲酰胺；微溶：乙醇

"Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic.

Target: Antibacterial

Pazufloxacin (T-3761), a new quinolone derivative, showed broad and potent antibacterial activity. T-3761 showed good efficacy in mice against systemic, pulmonary, and urinary tract infections with gram-positive and gram-negative bacteria, including quinolone-resistant Serratia marcescens and Pseudomonas aeruginosa. The in vivo activity of T-3761 was comparable to or greater than those of ofloxacin, ciprofloxacin, norfloxacin, and tosufloxacin against most infection models in mice. The activities of T-3761 were lower than those of tosufloxacin against gram-positive bacterial systemic and pulmonary infections in mice but not against infections with methicillin-resistant Staphylococcus aureus [1]. T-3761 had a broad spectrum of activity and had potent activity against gram-positive and -negative bacteria. The MICs of T-3761 against 90% of the methicillin-susceptible Staphylococcus aureus, methicillin-susceptible and -resistant Staphylococcus epidermidis, and Clostridium spp. tested were 0.39 to 6.25 micrograms/ml. The MBCs of T-3761 were either equal to or twofold greater than the MICs. The 50% inhibitory concentrations of T-3761 for DNA gyrases isolated from E. coli and P. aeruginosa were 0.88 and 1.9 micrograms/ml, respectively [2]."

包装：100mg，500mg，1g，10g，100g以及kg级别等公斤级大包装

纯度：99%

配送：惯例下常温**

包装：袋装

厂家：西安齐岳生物科技有限公司

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